bs-55057R

DATASHEET

Host: Rabbit

Target Protein: DPYSL2

Clonality: Polyclonal

Isotype: IgG

Entrez Gene: 1808

Swiss Prot: Q16555

Source: A synthetic peptide corresponding to a sequence within amino acids 400-500 of human DPYSL2 (NP_001377.1).

Purification: Purified by Protein A.

Storage Buffer: 0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Storage: Store at -20°C for 12 months.

Background:

This gene encodes a member of the collapsin response mediator protein family. Collapsin response mediator proteins form homo- and hetero-tetramers and facilitate neuron guidance, growth and polarity. The encoded protein promotes microtubule assembly and is required for Sema3A-mediated growth cone collapse, and also plays a role in synaptic signaling through interactions with calcium channels. This gene has been implicated in multiple neurological disorders, and hyperphosphorylation of the encoded protein may play a key role in the development of Alzheimer's disease. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Size: 100uL

Concentration: 1ug/ul

Applications: WB(1:300-5000)

Predicted Molecular Weight: 58kDa/62kDa

Cross Reactive Species: Human

For research use only. Not intended for diagnostic or therapeutic use.