bs-55058R

DATASHEET

Host: Rabbit

Target Protein: EDN1

Clonality: Polyclonal

Isotype: IgG

Entrez Gene: 1906

Swiss Prot: P05305

Source: Recombinant fusion protein containing a sequence corresponding to amino acids 18-212 of human EDN1 (NP_001946.3).

Purification: Purified by Protein A.

Storage Buffer: 0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Storage: Store at -20°C for 12 months.

Background:

This gene encodes a preproprotein that is proteolytically processed to generate a secreted peptide that belongs to the endothelin/sarafotoxin family. This peptide is a potent vasoconstrictor and its cognate receptors are therapeutic targets in the treatment of pulmonary arterial hypertension. Aberrant expression of this gene may promote tumorigenesis. Alternative splicing results in multiple transcript variants.

Size: 100uL

Concentration: 1ug/ul

Applications: WB(1:300-5000)
IHC(1:50-200)
IF(1:50-200)

Predicted Molecular Weight: 24kDa

Cross Reactive Species: Human
Mouse
Rat

For research use only. Not intended for diagnostic or therapeutic use.