bs-55065R

DATASHEET

Host: Rabbit

Target Protein: EIF4EBP1

Clonality: Polyclonal

Isotype: IgG

Entrez Gene: 1978

Swiss Prot: Q13541

Source: A synthetic peptide corresponding to a sequence within amino acids 50 to the C-terminus of human EIF4EBP1 (NP_004086.1).

Purification: Purified by Protein A.

Storage Buffer: 0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Storage: Store at -20°C for 12 months.

Background:

This gene encodes one member of a family of translation repressor proteins. The protein directly interacts with eukaryotic translation initiation factor 4E (eIF4E), which is a limiting component of the multisubunit complex that recruits 40S ribosomal subunits to the 5' end of mRNAs. Interaction of this protein with eIF4E inhibits complex assembly and represses translation. This protein is phosphorylated in response to various signals including UV irradiation and insulin signaling, resulting in its dissociation from eIF4E and activation of mRNA translation.

Size: 100uL

Concentration: 1ug/ul

Applications: WB(1:300-5000)
IF(ICC)(1:50-200)
IHC(1:50-200)
IF(1:50-200)

Predicted Molecular Weight: 12kDa

Cross Reactive Species: Human
Mouse
Rat

For research use only. Not intended for diagnostic or therapeutic use.