bs-5506R [Primary Antibody]
MAPK11(Thr180+Tyr182) Antibody
www.biossusa.com
[email protected]
800.501.7654 [DOMESTIC]
+1.781.569.5821 [INTERNATIONAL]
DATASHEET

Host: Rabbit

Target Protein: MAPK11 Thr180+Tyr182

Modification Site: Thr180+Tyr182

Clonality: Polyclonal

Isotype: IgG

Entrez Gene: 5600

Source: KLH conjugated synthetic phosphopeptide derived from human MAPK11 around the phosphorylation site of Thr180+Tyr182

Purification: Purified by Protein A.

Storage Buffer: 0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Storage: Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.

Background:

The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation, and development. MAPK11 is most closely related to p38 MAP kinase, both of which can be activated by proinflammatory cytokines and environmental stress. This kinase is activated through its phosphorylation by MAP kinase kinases (MKKs), preferably by MKK6. Transcription factor ATF2/CREB2 has been shown to be a substrate of this kinase.

Size: 100ul

Concentration: 1ug/ul

Applications: WB(WB=1:500-2000)
ELISA(ELISA=1:5000-10000)
IHC-P(IHC-P=1:100-500)
IHC-F(IHC-F=1:100-500)
IF(IF=1:100-500)
Flow-Cyt(Flow-Cyt=1μg /test)
ICC/IF(ICC/IF=1:100)

Predicted Molecular Weight: 41


Cross Reactive Species: Human

Predicted Cross Reactive Species: Mouse
Rat
Dog
Cow

For research use only. Not intended for diagnostic or therapeutic use.

VALIDATION IMAGES

Formalin-fixed and paraffin embedded human colon carcinoma labeled with Anti-phospho-MAPK11(Thr180+Tyr182) Polyclonal Antibody, Unconjugated (bs-5506R) at 1:200 followed by conjugation to the secondary antibody and DAB staining.