DATASHEET
Host:
Rabbit
Target Protein:
IKBKG
Clonality:
Polyclonal
Isotype:
IgG
Entrez Gene:
8517
Swiss Prot:
Q9Y6K9
Source:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-419 of human IKBKG (NP_003630.1).
Purification:
Purified by Protein A.
Storage Buffer:
0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Storage:
Store at -20°C for 12 months.
Background:
This gene encodes the regulatory subunit of the inhibitor of kappaB kinase (IKK) complex, which activates NF-kappaB resulting in activation of genes involved in inflammation, immunity, cell survival, and other pathways. Mutations in this gene result in incontinentia pigmenti, hypohidrotic ectodermal dysplasia, and several other types of immunodeficiencies. A pseudogene highly similar to this locus is located in an adjacent region of the X chromosome.
VALIDATION IMAGES
Lane 1: A549 cell lysates; Lane 2: Mouse Liver lysates probed with IKBKG Polyclonal Antibody, Unconjugated (bs-55110R) at 1:1000 dilution and 4˚C overnight incubation. Followed by conjugated secondary antibody incubation at 1:20000 for 60 min at 37˚C.
Lane 1: 293T cell lysates; Lane 2: IKBKG knockout (KO) 293T cell lysates probed with IKBKG Polyclonal Antibody, Unconjugated (bs-55110R) at 1:1000 dilution and 4˚C overnight incubation. Followed by conjugated secondary antibody incubation at 1:20000 for 60 min at 37˚C.