bs-55125R

DATASHEET

Host: Rabbit

Target Protein: LITAF

Clonality: Polyclonal

Isotype: IgG

Entrez Gene: 9516

Swiss Prot: Q99732

Source: Recombinant fusion protein containing a sequence corresponding to amino acids 1-161 of human LITAF (NP_004853.2).

Purification: purified by Protein A.

Storage Buffer: 0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Storage: Store at -20°C for 12 months.

Background:

Lipopolysaccharide is a potent stimulator of monocytes and macrophages, causing secretion of tumor necrosis factor-alpha (TNF-alpha) and other inflammatory mediators. This gene encodes lipopolysaccharide-induced TNF-alpha factor, which is a DNA-binding protein and can mediate the TNF-alpha expression by direct binding to the promoter region of the TNF-alpha gene. The transcription of this gene is induced by tumor suppressor p53 and has been implicated in the p53-induced apoptotic pathway. Mutations in this gene cause Charcot-Marie-Tooth disease type 1C (CMT1C) and may be involved in the carcinogenesis of extramammary Paget's disease (EMPD). Multiple alternatively spliced transcript variants have been found for this gene.

Size: 100ul

Concentration: Lot Dependent

Applications: WB(1:300-5000)
IP(1-2ug)
IHC(1:50-200)
IHC-P(1:200-400)

Predicted Molecular Weight: 15kDa/17kDa/23kDa

Cross Reactive Species: Human
Mouse

For research use only. Not intended for diagnostic or therapeutic use.