bs-55164R-BF680

DATASHEET

Host: Rabbit

Target Protein: PARP1

Specificity: KO-Validated

Immunogen Range: 81-390/1014

Clonality: Polyclonal

Isotype: IgG

Entrez Gene: 142

Swiss Prot: P09874

Source: Recombinant human PARP1

Purification: purified by Protein A.

Storage Buffer: Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Storage: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Background:

This gene encodes a chromatin-associated enzyme, poly(ADP-ribosyl)transferase, which modifies various nuclear proteins by poly(ADP-ribosyl)ation. The modification is dependent on DNA and is involved in the regulation of various important cellular processes such as differentiation, proliferation, and tumor transformation and also in the regulation of the molecular events involved in the recovery of cell from DNA damage. In addition, this enzyme may be the site of mutation in Fanconi anemia, and may participate in the pathophysiology of type I diabetes.

Conjugation: AbBy Fluor-680

Excitation/ Emission: 679nm/702nm

Size: 100ul

Concentration: 1mg/ml

Applications: WB(1:500-2000)
IHC-F(1:100-500)
IF(1:100-500)
IHC-P(1:100-500)
ICC/IF(1:100-200)
Flow-Cyt(1:50-100)

Predicted Molecular Weight: 113 kDa

Cross Reactive Species: Human
Mouse
Rat

Predicted Cross Reactive Species: Human
Mouse
Rat

For research use only. Not intended for diagnostic or therapeutic use.