bs-5714R [Primary Antibody]
OVCA1 Polyclonal Antibody
[email protected]
800.501.7654 [DOMESTIC]
+1.781.569.5821 [INTERNATIONAL]

Host: Rabbit

Target Protein: OVCA1

Clonality: Polyclonal

Isotype: IgG

Entrez Gene: 1801

Source: KLH conjugated synthetic peptide derived from human OVCA1

Purification: Purified by Protein A.

Storage: Aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for 12 months.

Background: OVCA1 is required for the first step in the synthesis of diphthamide, a unique posttranslationally modified histidine found only in translation elongation factor-2 (EEF2; MIM 130610). This modification is conserved from archaebacteria to humans and serves as the target for ADP-ribosylation and inactivation of EEF2 by diphtheria toxin (DT) and Pseudomonas exotoxin A. OVCA1 is one of several enzymes involved in synthesis of diphthamide in EEF2.

Size: 100ul

Concentration: 1ug/ul

Applications: WB(1:300-1000)

Cross Reactive Species: Human

For research use only. Not intended for diagnostic or therapeutic use.

  • Lin Y et al. The tumor suppressor OVCA1 is a short half‑life protein degraded by the ubiquitin‑proteasome pathway. Oncol Lett. 2019 Feb;17(2):2328-2334.Read more>>