bs-5911R [Primary Antibody]
Cyclophilin B Polyclonal Antibody
www.biossusa.com
[email protected]
800.501.7654 [DOMESTIC]
+1.781.569.5821 [INTERNATIONAL]
DATASHEET

Host: Rabbit

Target Protein: Cyclophilin B

Immunogen Range: 21-120/216


Clonality: Polyclonal

Isotype: IgG

Entrez Gene: 5479

Source: KLH conjugated synthetic peptide derived from human Cyclophilin B

Purification: Purified by Protein A.

Storage Buffer: 0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Storage: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Background:

The cyclophilins are a conserved class of proteins that bind the immunosuppressive drug cyclosporin A (CsA) with high affinity. CsA blocks helper T-cell activation at a step between T-cell receptor stimulation and the transcriptional activation of cytokine genes. Cyclophilins from many species possess peptidyl-prolyl cis-trans isomerase (PPIase) activity that is blocked by CsA and therefore may be relevant in CsA-mediated immunosuppression.

Size: 100ul

Concentration: 1ug/ul

Applications: WB(1:300-5000)
ELISA(1:500-1000)
IF(IHC-P)(1:50-200)

Predicted Molecular Weight: 20


Cross Reactive Species: Human
Rat
Bovine

Predicted Cross Reactive Species: Mouse
Dog
Cow
Pig
Horse
Rabbit

For research use only. Not intended for diagnostic or therapeutic use.

PRODUCT SPECIFIC PUBLICATIONS
  • Zhao et al. Cyclophilin B facilitates the replication of Orf virus. (2017) Virol.J. 14:114Read more>>