bs-5980R [Primary Antibody]
n-Myc Polyclonal Antibody
www.biossusa.com
[email protected]
800.501.7654 [DOMESTIC]
+1.781.569.5821 [INTERNATIONAL]
DATASHEET

Host: Rabbit

Target Protein: n-Myc

Immunogen Range: 401-464/464


Clonality: Polyclonal

Isotype: IgG

Entrez Gene: 4613

Swiss Prot: P04198

Source: KLH conjugated synthetic peptide derived from human n-Myc

Purification: Purified by Protein A.

Storage Buffer: 0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Storage: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Background:

This gene is a member of the MYC family and encodes a protein with a basic helix-loop-helix (bHLH) domain. This protein is located in the nucleus and must dimerize with another bHLH protein in order to bind DNA. Amplification of this gene is associated with a variety of tumors, most notably neuroblastomas. [provided by RefSeq, Jul 2008].

Size: 100ul

Concentration: 1ug/ul

Applications: WB()
IHC-P(1:200-400)

Predicted Molecular Weight: 49


Cross Reactive Species: Human
Mouse

Predicted Cross Reactive Species: Rat
Cow
Pig

For research use only. Not intended for diagnostic or therapeutic use.

PRODUCT SPECIFIC PUBLICATIONS
  • Ramraj, Satish Kumar, et al. "Serum-circulating miRNAs predict neuroblastoma progression in mouse model of high-risk metastatic disease."Oncotarget 7.14 (2016): 18605-18619.Read more>>
  • Shi, Zhen-Hua, et al. "Mitochondrial ferritin, a new target for inhibiting neuronal tumor cell proliferation." Cellular and Molecular Life Sciences 72.5 (2015): 983-997.Read more>>
  • Guosheng Wu. et al. Non-muscle myosin II knockdown improves survival and therapeutic effects of implanted bone marrow-derived mesenchymal stem cells in lipopolysaccharide-induced acute lung injury. Ann Transl Med. 2021 Feb; 9(3): 262Read more>>
VALIDATION IMAGES

Formalin-fixed and paraffin embedded human colon carcinoma labeled with Anti-n-Myc Polyclonal Antibody, Unconjugated (bs-5980R) at 1:200 followed by conjugation to the secondary antibody and DAB staining