bs-60179C
[Life Science]
GSK-LSD1 --- LSD1 Inhibitor
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support@biossusa.com
800.501.7654 [DOMESTIC]
+1.781.569.5821 [INTERNATIONAL]
DATASHEET
Formulation powder
Storage: Store in dry, dark place at -20C for 1 year.
Product Information:
Molecular Weight: 289.24
Formula: C14 H22 Cl2 N2
CAS Number: 2102933-95-7
InChi Key: PJFZOGMSPBHPNS-WICJZZOFSA-N
InChi: InChI=1S/C14H20N2.2ClH/c1-2-4-11(5-3-1)13-10-14(13)16-12-6-8-15-9-7-12;;/h1-5,12-16H,6-10H2;2*1H/t13-,14+;;/m0../s1
Smiles: Cl.Cl.C1[C@H]([C@@H]1NC1CCNCC1)C1C=CC=CC=1
Purity: 98.0
Solubility: DMSO up to 100 mM
Appearance: Solid Power.
Shelf Life: 1.0 years
Formula: C14 H22 Cl2 N2
CAS Number: 2102933-95-7
InChi Key: PJFZOGMSPBHPNS-WICJZZOFSA-N
InChi: InChI=1S/C14H20N2.2ClH/c1-2-4-11(5-3-1)13-10-14(13)16-12-6-8-15-9-7-12;;/h1-5,12-16H,6-10H2;2*1H/t13-,14+;;/m0../s1
Smiles: Cl.Cl.C1[C@H]([C@@H]1NC1CCNCC1)C1C=CC=CC=1
Purity: 98.0
Solubility: DMSO up to 100 mM
Appearance: Solid Power.
Shelf Life: 1.0 years
Description:
GSK-LSD1 is a highly potent, specific and irreversible inhibitor of Lysine Specific Demethylase-1 (LSD1). It inhibits LSD1 in biochemical assay with an IC50 ~16 nM, and is > 1000 fold selective over other closely related FAD utilizing enzymes (i.e. LSD2, MAO-A, MAO-B). GSK-LSD1 induces gene expression changes in cancer cell lines (average EC50 < 5 nM) and inhibits cancer cell line growth (average EC50 < 5 nM).
Size: 10mg, 2mg
Applications: Life Science
For research use only. Not intended for diagnostic or therapeutic use.