bs-6304R-A680 [Conjugated Primary Antibody]
IFN-Alpha Polyclonal Antibody, ALEXA FLUOR® 680 Conjugated
www.biossusa.com
[email protected]
800.501.7654 [DOMESTIC]
+1.781.569.5821 [INTERNATIONAL]
DATASHEET

Host: Rabbit

Target Protein: IFN-Alpha

Specificity: This antibody will detect Human IFN-Alpha subtypes 2,4,5,6,7,8,10,14,16,17 and has lower affinity for IFNA1/13. This antibody will detect Mouse IFN-Alpha subtypes 1,2,5,7,12,13,14,16

Immunogen Range: 101-189/189


Clonality: Polyclonal

Isotype: IgG

Entrez Gene: 3441

Swiss Prot: P05014

Source: KLH conjugated synthetic peptide derived from human IFNA4

Purification: Purified by Protein A.

Storage Buffer: Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Storage: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Background:

Interferon-_ (IFN-_, also known as IFN-alpha, IFN-a, IFNA and Interferon-alpha) is a type I interferon and exists as 13 subtypes: IFN-_ 1, 2, 4, 5, 6, 7, 8, 10, 13, 14, 16, 17 and 21. They are mainly produced by virus-infected cells after sensing the presence of danger signals such as viral DNA or RNA. The binding of IFN-_ to its receptor initiates an anti-viral response, but also anti-tumor effects have been shown. A key producer of type I interferons is the plasmacytoid dendritic cell.

Conjugation: ALEXA FLUOR® 680

Excitation/ Emission: 679nm/702nm

Size: 100ul

Concentration: 1ug/ul

Applications: WB(1:300-5000)
IF(IHC-P)(1:50-200)
IF(IHC-F)(1:50-200)
IF(ICC)(1:50-200)

Predicted Molecular Weight: 22


Cross Reactive Species: Mouse

Predicted Cross Reactive Species: Human

For research use only. Not intended for diagnostic or therapeutic use.

PRODUCT SPECIFIC PUBLICATIONS
  • Xueer Liu. et al. Lidocaine inhibits influenza a virus replication by up-regulating IFN4 via TBK1-IRF7 and JNK-AP1 signaling pathways. INT IMMUNOPHARMACOL. 2023 Feb;115:109706Read more>>
  • Xiaoxuan Zhao. et al. Demystifying the impact of prenatal tobacco exposure on the placental immune microenvironment: Avoiding the tragedy of mending the fold after death. JOURNAL OF CELLULAR AND MOLECULAR MEDICINE. 2023 SepRead more>>
VALIDATION IMAGES