bs-6377R [Primary Antibody]
Deformed Epidermal Autoregulatory Factor 1 Antibody
www.biossusa.com
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DATASHEET

Host: Rabbit

Target Protein: Deformed Epidermal Autoregulatory Factor 1

Immunogen Range: 211-310/565


Clonality: Polyclonal

Isotype: IgG

Entrez Gene: 10522

Source: KLH conjugated synthetic peptide derived from human Deformed Epidermal Autoregulatory Factor 1

Purification: Purified by Protein A.

Storage Buffer: 0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Storage: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Background:

Suppressin, also known as DEAF1 is a transcription factor required for embryonic development. Suppressin contains one SAND domain and one C-terminal MYND-type zinc finger. It interacts with LMO4 and CLIM-2, suggesting that it plays a role mediating cell fate and embryonic pattern formation. Suppressin is expressed in a variety of tissues and localizes to the nucleus. Several isoforms exist due to alternative splicing and, depending on the isoform, Suppressin is secreted in some cell types. Secreted Suppressin can function to inhibit cell proliferation, arresting cells in the G0 or G1 phase. Mutations in the gene encoding Suppressin may result in a growth advantage leading to the development and progression of neoplasia. This suggest that Supressin is a potential target for cancer therapy.

Size: 100ul

Concentration: 1ug/ul

Applications: WB(1:300-5000)
ELISA(1:500-1000)
IF(IHC-P)(1:50-200)

Predicted Molecular Weight: 59


Cross Reactive Species: Mouse

Predicted Cross Reactive Species: Rat
Dog
Cow
Horse
Chicken

For research use only. Not intended for diagnostic or therapeutic use.

VALIDATION IMAGES

Mouse pancreas lysates; probed with Deformed Epidermal Autoregulatory Factor 1 Polyclonal Antibody, unconjugated (bs-6377R) at 1:2000 overnight at 4°C followed by a conjugated secondary antibody for 60 minutes at 37°C.