bs-6468R [Primary Antibody]
kir 6.1 Polyclonal Antibody
www.biossusa.com
[email protected]
800.501.7654 [DOMESTIC]
+1.781.569.5821 [INTERNATIONAL]
DATASHEET

Host: Rabbit

Target Protein: kir 6.1

Immunogen Range: 61-160/424


Clonality: Polyclonal

Isotype: IgG

Entrez Gene: 3764

Swiss Prot: Q15842

Source: KLH conjugated synthetic peptide derived from human kir 6.1

Purification: Purified by Protein A.

Storage Buffer: 0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Storage: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Background:

This potassium channel is controlled by G proteins. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. Can be blocked by external barium (By similarity).

Size: 100ul

Concentration: 1ug/ul

Applications: WB(1:300-5000)
ELISA(1:500-1000)
IHC-P(1:200-400)
IHC-F(1:100-500)
IF(IHC-P)(1:50-200)
IF(IHC-F)(1:50-200)
IF(ICC)(1:50-200)

Predicted Molecular Weight: 48


Cross Reactive Species: Rat

Predicted Cross Reactive Species: Human
Mouse
Cow
Pig
Chicken
Rabbit

For research use only. Not intended for diagnostic or therapeutic use.

PRODUCT SPECIFIC PUBLICATIONS
  • Horii K et al. ATP-dependent potassium channels contribute to motor regulation of esophageal striated muscle in rats. J Vet Med Sci. 2019 Jul 9. Read more>>
  • Hessah Al-Shammari. et al. Expression and function of mechanosensitive ion channels in human valve interstitial cells. Plos One. 2020 Oct;15(10):e0240532Read more>>
VALIDATION IMAGES

Rat heart lysates probed with kir 6.1 Polyclonal Antibody, Unconjugated (bs-6468R) at 1:1000 dilution and 4˚C overnight incubation. Followed by conjugated secondary antibody incubation at 1:20000 for 60 min at 37˚C.


Lane 1: Mouse Liver tissue lysates; Lane 2: Mouse Cerebrum tissue lysates; Lane 3: Rat Liver tissue lysates; Lane 4: Rat Skin tissue lysates; Lane 5: Rat Cerebrum tissue lysates probed with kir 6.1 Polyclonal Antibody, Unconjugated (bs-6468R) at 1:1000 dilution and 4°C overnight incubation. Followed by conjugated secondary antibody incubation at room temperature for 60 min.