Target Protein: GCET2
Immunogen Range: 31-130/178
Entrez Gene: 257144
Swiss Prot: Q8N6F7
Source: KLH conjugated synthetic peptide derived from human GCET2
Purification: Purified by Protein A.
Storage Buffer: Aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide.
Storage Condition: Store at -20°C for 12 months..
Background: Involved in the negative regulation of lymphocyte motility. It mediates the migration-inhibitory effects of IL6. Serves as a positive regulator of the RhoA signaling pathway. Enhancement of RhoA activation results in inhibition of lymphocyte and lymphoma cell motility by activation of its downstream effector ROCK. Is a regulator of B-cell receptor signaling, that acts through SYK kinase activation.
Cross Reactive Species:
Predicted Cross Reactive Species: Human
For research use only. Not intended for diagnostic or therapeutic use.