bs-6695R-A350 [Conjugated Primary Antibody]
Cytochrome P450 17A1 Polyclonal Antibody, ALEXA FLUOR® 350 Conjugated
www.biossusa.com
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DATASHEET

Host: Rabbit

Target Protein: Cytochrome P450 17A1

Immunogen Range: 24-65/508


Clonality: Polyclonal

Isotype: IgG

Entrez Gene: 1586

Swiss Prot: P05093

Source: KLH conjugated synthetic peptide derived from human Cytochrome P450 17A1

Purification: Purified by Protein A.

Storage Buffer: Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Storage: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Background:

Conversion of pregnenolone and progesterone to their 17-alpha-hydroxylated products and subsequently to dehydroepiandrosterone (DHEA) and androstenedione. Catalyzes both the 17-alpha-hydroxylation and the 17,20-lyase reaction. Involved in sexual development during fetal life and at puberty.

Conjugation: ALEXA FLUOR® 350

Excitation/ Emission: 346nm/442nm

Size: 100ul

Concentration: 1ug/ul

Applications: WB(1:300-5000)

Predicted Molecular Weight: 57


Cross Reactive Species: Mouse
Rat
Others

Predicted Cross Reactive Species: Human
Cow
Sheep
Horse
Rabbit

For research use only. Not intended for diagnostic or therapeutic use.

PRODUCT SPECIFIC PUBLICATIONS
  • Wilsher, Sandra, et al. "Ovarian and placental morphology and endocrine function in the pregnant giraffe (Giraffa camelopardalis)." Reproduction (2013).Read more>>
  • Han, Wentao, et al. "Seasonal Expression of P450c17 and 5α-reductase-2 in the Scented Gland of Male Muskrats (Ondatra zibethicus)." General and Comparative Endocrinology (2017).Read more>>
  • Zhang, Weidong, et al. "Decrease in male mouse fertility by hydrogen sulfide and/or ammonia can Be inheritable." Chemosphere (2017).Read more>>
  • Lu-ming Wu. et al. Dulaglutide, a long-acting GLP-1 receptor agonist, can improve hyperandrogenemia and ovarian function in DHEA-induced PCOS rats. Peptides. 2021 Nov;145:170624Read more>>
VALIDATION IMAGES