bs-6716C [Life Science]
PTC-028
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Formulation Powder

Storage: Store in dry, dark place at -20C for 1 year.

Product Information:

Molecular Weight: 405.32

Formula: C19 H12 F5 N5

CAS Number: 1782970-28-8

InChi Key: JEZGPBWIZWPDHP-UHFFFAOYSA-N

InChi: InChI=1S/C19H12F5N5/c1-10-26-15-6-13(20)14(21)7-16(15)29(10)18-9-25-8-17(28-18)27-12-4-2-11(3-5-12)19(22,23)24/h2-9H,1H3,(H,27,28)

Smiles: CC1=NC2=CC(F)=C(F)C=C2N1C1C=NC=C(NC2C=CC(=CC=2)C(F)(F)F)N=1

Purity: 98.0

Solubility: DMSO: 81 mg/mL(199.84 mM).

Appearance: Solid Power.

Shelf Life: 1.0 years

Description:

PTC-028 is an orally bioavailable compound that decreases BMI-1 levels by posttranslational modification. In vivo, orally administered PTC-028, as a single agent, exhibits significant antitumor activity comparable with the standard cisplatin/paclitaxel therapy in an orthotopic mouse model of ovarian cancer.

Size: 10mg,2mg

Applications: Life Science()

For research use only. Not intended for diagnostic or therapeutic use.