bs-6717R [Primary Antibody]
NALP2 Polyclonal Antibody
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Host: Rabbit

Target Protein: NALP2

Clonality: Polyclonal

Isotype: IgG

Entrez Gene: 55655

Source: KLH conjugated synthetic peptide derived from human NALP2/NACHT, LRR and PYD domains-containing protein 2

Purification: Purified by Protein A.

Storage Buffer: 0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Storage: Store at -20°C for 12 months.

Background:

NALP proteins, such as NALP2, are characterized by an N-terminal pyrin (MIM 608107) domain (PYD) and are involved in the activation of caspase-1 (CASP1; MIM 147678) by Toll-like receptors (see TLR4; MIM 603030). They may also be involved in protein complexes that activate proinflammatory caspases (Tschopp et al., 2003 [PubMed 12563287]).[supplied by OMIM, Mar 2008].

Size: 100µL

Concentration: 1ug/ul

Applications: WB(1:300-5000)
IHC-P(1:200-400)
IF(IHC-P)(1:50-200)

Cross Reactive Species: Human
Mouse
Rat

For research use only. Not intended for diagnostic or therapeutic use.

VALIDATION IMAGES

Formalin-fixed and paraffin embedded rat brain labeled with Rabbit Anti NALP2/PAN1/PYPAF2 Polyclonal Antibody, Unconjugated (bs-6717R) at 1:200 followed by conjugation to the secondary antibody and DAB staining


Lane 1: Mouse Thymus tissue lysates; Lane 2: Mouse Ovary tissue lysates; Lane 3: Rat Placenta tissue lysates; Lane 4: Human MCF-7 cell lysates probed with NALP2 Polyclonal Antibody, Unconjugated (bs-6717R) at 1:1000 dilution and 4°C overnight incubation. Followed by conjugated secondary antibody incubation at room temperature for 60 min.