bs-6933R [Primary Antibody]
MICA+MICB Polyclonal Antibody
www.biossusa.com
[email protected]
800.501.7654 [DOMESTIC]
+1.781.569.5821 [INTERNATIONAL]
DATASHEET

Host: Rabbit

Target Protein: MICA+MICB

Immunogen Range: 81-180/383


Clonality: Polyclonal

Isotype: IgG

Entrez Gene: 100507436, 4277

Swiss Prot: Q29983, Q29980

Source: KLH conjugated synthetic peptide derived from human MICB

Purification: Purified by Protein A.

Storage Buffer: 0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Storage: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Background:

Acts as a stress-induced self-antigen that is recognized by gamma delta T-cells. Ligand for the KLRK1/NKG2D receptor. Binding to KLRK1 leads to cell lysis.

Size: 100ul

Concentration: 1ug/ul

Applications: ELISA(1:500-1000)
IHC-P(1:200-400)
IHC-F(1:100-500)
IF(IHC-P)(1:50-200)
IF(IHC-F)(1:50-200)
IF(ICC)(1:50-200)

Predicted Molecular Weight: 40


Cross Reactive Species: Human

For research use only. Not intended for diagnostic or therapeutic use.

PRODUCT SPECIFIC PUBLICATIONS
  • Battistella et al. The High Expression of the microRNA 17-92 Cluster and its Paralogs, and the Downregulation of the Target Gene PTEN, Is Associated with Primary Cutaneous B-Cell Lymphoma Progression. (2015) J.Invest.Dermato. 135:1659-67Read more>>
  • Pernilla Israelsson. et al. NKG2D-mediated cytotoxicity improves after primary surgery for high-grade serous ovarian cancer. AM J REPROD IMMUNOL. 2022 NovRead more>>
VALIDATION IMAGES

Formalin-fixed and paraffin embedded human lung carcinoma labeled with Anti-MICB Polyclonal Antibody, Unconjugated (bs-6933R) at 1:200 followed by conjugation to the secondary antibody and DAB staining.