bs-6962C
[Life Science]
IACS-9571
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support@biossusa.com
800.501.7654 [DOMESTIC]
+1.781.569.5821 [INTERNATIONAL]
DATASHEET
Formulation powder
Storage: Store in dry, dark place at -20C for 1 year.
Product Information:
Molecular Weight: 642.76
Formula: C32 H42 N4 O8 S
CAS Number: 1800477-30-8
InChi Key: HYQBRUSSCIAOOD-UHFFFAOYSA-N
InChi: InChI=1S/C32H42N4O8S/c1-8-14-42-22-16-23(43-15-10-9-13-34(2)3)18-24(17-22)44-30-21-28-27(35(4)32(37)36(28)5)20-26(30)33-45(38,39)25-11-12-29(40-6)31(19-25)41-7/h11-12,16-21,33H,8-10,13-15H2,1-7H3
Smiles: CN(C)CCCCOC1C=C(C=C(C=1)OCCC)OC1=CC2=C(C=C1NS(=O)(=O)C1C=CC(OC)=C(C=1)OC)N(C)C(=O)N2C
Purity: 98.0
Solubility: Soluble in DMSO, not in water
Appearance: Solid Power.
Shelf Life: 1.0 years
Formula: C32 H42 N4 O8 S
CAS Number: 1800477-30-8
InChi Key: HYQBRUSSCIAOOD-UHFFFAOYSA-N
InChi: InChI=1S/C32H42N4O8S/c1-8-14-42-22-16-23(43-15-10-9-13-34(2)3)18-24(17-22)44-30-21-28-27(35(4)32(37)36(28)5)20-26(30)33-45(38,39)25-11-12-29(40-6)31(19-25)41-7/h11-12,16-21,33H,8-10,13-15H2,1-7H3
Smiles: CN(C)CCCCOC1C=C(C=C(C=1)OCCC)OC1=CC2=C(C=C1NS(=O)(=O)C1C=CC(OC)=C(C=1)OC)N(C)C(=O)N2C
Purity: 98.0
Solubility: Soluble in DMSO, not in water
Appearance: Solid Power.
Shelf Life: 1.0 years
Description:
IACS-9571 is a potent and selective inhibitor TRIM24 and BRPF1. IACS-9571 has low nanomolar affinities for TRIM24 and BRPF1 (ITC Kd = 31 nM and 14 nM, respectively). With its excellent cellular potency (EC50 = 50 nM) and favorable pharmacokinetic properties (F = 29%), IACS-9571 is a high-quality chemical probe for the evaluation of TRIM24 and/or BRPF1 bromodomain function in vitro and in vivo.
Size: 10mg, 2mg
Applications: Life Science
For research use only. Not intended for diagnostic or therapeutic use.