bs-70029S

DATASHEET

Host: Sheep

Target Protein: Calretinin

Specificity: Specific for endogenous levels of the ~29 kDa calretinin protein in Western blots of rat brain lysate. The antibody also works well for immunohistochemistry on formalin or paraformaldehyde perfused rat brain tissue sections.

Clonality: Polyclonal

Isotype: IgG

Entrez Gene: 117059

Swiss Prot: P47728

Source: Purified guinea pig calretinin.

Purification: Purified by Protein G.

Storage Buffer: 10 mM Tris, 100 mM NaCl

Storage: Recommended that the undiluted antibody be aliquoted into smaller working volumes (10-30 uL/vial depending on usage) upon arrival and stored long term at -20° C or -80° C, while keeping a working aliquot stored at 4° C for short term. Avoid freeze/thaw cy

Background:

Calretinin is a calcium-binding protein involved in calcium signaling. It is abundantly expressed throughout the central nervous system, retina and many other tissues. Studies have shown that calretinin may play a role in neuroprotection by buffering intracellular calcium (Lukas and Jones 1994, Weisenhorn et al., 1996). Additionally, calretinin selectively stains mesothelial cells thus making it an important marker for differentiating malignant mesothelioma from carcinomas (Attanoos et al., 2000).

Size: 100µL

Concentration: Lot Dependent

Applications: WB(1:300-5000)
IHC

Predicted Molecular Weight: 29

Cross Reactive Species: Rat

Predicted Cross Reactive Species: Human
Mouse
Non-Human Primate

For research use only. Not intended for diagnostic or therapeutic use.