DATASHEET
Host:
Rabbit
Target Protein:
STK31
Immunogen Range:
201-300/1019
Clonality:
Polyclonal
Isotype:
IgG
Entrez Gene:
56164
Swiss Prot:
Q9BXU1
Source:
KLH conjugated synthetic peptide derived from human STK31
Purification:
Purified by Protein A.
Storage Buffer:
0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Storage:
Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.
Background:
STK31 (Serine/threonine protein kinase 31) is similar to a mouse gene that encodes a putative protein kinase with a tudor domain, and shows testis specific expression. Alternative splicing results in multiple transcript variants encoding different isoforms. Protein kinases are enzymes that transfer a phosphate group from a phosphate donor, generally the g phosphate of ATP, onto an acceptor amino acid in a substrate protein. By this basic mechanism, protein kinases mediate most of the signal transduction in eukaryotic cells, regulating cellular metabolism, transcription, cell cycle progression, cytoskeletal rearrangement and cell movement, apoptosis, and differentiation. With more than 500 gene products, the protein kinase family is one of the largest families of proteins in eukaryotes.
PRODUCT SPECIFIC PUBLICATIONS
- Wang, Yandi, et al. "Regulation of steroid hormones and energy status with cysteamine and its effect on spermatogenesis." Toxicology and Applied Pharmacology 313 (2016): 149-158.Read more>>
VALIDATION IMAGES
Formalin-fixed and paraffin embedded rat testis labeled with Rabbit Anti-STK31 Polyclonal Antibody, Unconjugated (bs-7051R) at 1:200 followed by conjugation to the secondary antibody and DAB staining
Lane 1: MCF-7 cell lysates; Lane 2: A431 cell lysates probed with STK31 Polyclonal Antibody, Unconjugated (bs-7015R) at 1:1000 dilution and 4˚C overnight incubation. Followed by conjugated secondary antibody incubation at 1:20000 for 60 min at 37˚C.
Lane 1: Mouse testis lysates; Lane 2: A549 cell lysates probed with STK31 Polyclonal Antibody, Unconjugated (bs-7015R) at 1:1000 dilution and 4˚C overnight incubation. Followed by conjugated secondary antibody incubation at 1:20000 for 60 min at 37˚C.