bs-70205R

DATASHEET

Host: Rabbit

Target Protein: Olig1

Specificity: Specific for endogenous levels of the ~27 kDa Olig1 protein.

Clonality: Polyclonal

Isotype: IgG

Entrez Gene: 50914

Swiss Prot: Q9JKN5

Source: Recombinant mouse Olig1.

Purification: Purified by Protein A.

Storage Buffer: 100 mM Glycine, 200 mM Tris, pH 8.0

Storage: Recommended that the undiluted antibody be aliquoted into smaller working volumes (10-30 uL/vial depending on usage) upon arrival and stored long term at -20° C or -80° C, while keeping a working aliq

Background:

Olig genes have been identified as the earliest known markers of oligodendrocyte lineage determination to date (Zhou et al., 2000). Olig1 is a transcription factor which promotes formation and maturation of oligodendrocytes, especially within the brain. It is expressed in the ventral spinal cord as early as 9.5 dpc and by 15.5 dpc, olig1 is dispersed throughout the gray matter. In the postnatal brain, it is present preferentially in the white matter, such as corpus callosum and cerebellar medulla. Olig1 has been demonstrated as necessary in the repair of brain lesions in patients with multiple sclerosis (Arnett et al. 2004).

Size: 100ul

Concentration: Lot Dependent

Predicted Molecular Weight: 27

Cross Reactive Species: Human
Mouse
Rat

For research use only. Not intended for diagnostic or therapeutic use.