bs-70309R

DATASHEET

Host: Rabbit

Target Protein: Vesicular GABA transporter (VGAT)

Specificity: Specific for endogenous levels of the ~53 kDa VGAT protein.

Clonality: Polyclonal

Isotype: IgG

Entrez Gene: 83612

Swiss Prot: O35458

Source: Synthetic peptide corresponding to amino acid residues from the N-terminal region of rat VGAT, conjugated to keyhole limpet hemocyanin (KLH).

Purification: Antigen Affinity purification from Pooled whole antiserum

Storage Buffer: 10 mM HEPES (pH 7.5), 150 mM NaCl, 100 µg per ml BSA and 50% glycerol.

Storage: Storage at -20°C is recommended, as aliquots may be taken without freeze/thawing due to presence of 50% glycerol. Stable for at least 1 year at -20°C.

Background:

The Vesicular GABA Amino Acid Transporter (VGAT) is responsible for transport of the inhibitory neurotransmitter into synaptic vesicles(McIntire et al., 1997). The VGAT protein (also known as the Vesicular Inhibitory Amino Aid Transporter or VIAAT) is expressed in synaptic vesicles of both glycine and GABAergic synapses throughout the CNS (Chaudhry et al., 1998). Expression of the VGAT protein changes during development and also in response to patterns of neuronal activity (De et al., 2005).

Size: 100ul

Concentration: Lot Dependent

Predicted Molecular Weight: 53

Cross Reactive Species: Mouse
Rat
Chicken
Xenopus

Predicted Cross Reactive Species: Dog
Bovine
Non-Human Primate

For research use only. Not intended for diagnostic or therapeutic use.