bs-70314S

DATASHEET

Host: Sheep

Target Protein: Vesicular Monoamine Transporter 2, C-terminus (VMAT2)

Specificity: Specific for endogenous levels of the ~57 kDa VMAT2 protein.

Clonality: Polyclonal

Isotype: IgG

Entrez Gene: 6571

Swiss Prot: Q05940

Source: Synthetic peptide corresponding to amino acid residues from the intracellular C-terminal region of human VMAT2, conjugated to keyhole limpet hemocyanin (KLH).

Purification: Antigen Affinity purification from Pooled whole antiserum

Storage Buffer: 10 mM HEPES (pH 7.5), 150 mM NaCl, 100 µg per ml BSA and 50% glycerol.

Storage: Storage at -20°C is recommended, as aliquots may be taken without freeze/thawing due to presence of 50% glycerol. Stable for at least 1 year at -20°C.

Background:

Vesicular neurotransmitter transporters sequester the transmitters into synaptic vesicles (Erickson et al., 1996). The vesicular monoamine transporter 2 (VMAT2) is responsible for catecholamine and serotonin storage in central synapses. Antibodies specific for VMAT have been used to monitor expression of the transporter during development and in aging and can be effectively used as a marker for monoamine terminals (Haycock et al., 2003; Witkovsky et al., 2005).

Size: 100µL

Concentration: Lot Dependent

Applications: WB(1:300-5000)

Predicted Molecular Weight: 57

Cross Reactive Species: Human
Rat

For research use only. Not intended for diagnostic or therapeutic use.