bs-7035C
[Life Science]
Brigatinib-analog
www.biossusa.com
support@biossusa.com
800.501.7654 [DOMESTIC]
+1.781.569.5821 [INTERNATIONAL]
support@biossusa.com
800.501.7654 [DOMESTIC]
+1.781.569.5821 [INTERNATIONAL]
DATASHEET
Formulation powder
Storage: Store in dry, dark place at -20C for 1 year.
Product Information:
Molecular Weight: 529.01
Formula: C26 H34 Cl N6 O2 P
CAS Number: 1197958-12-5
InChi Key: OVDSPTSBIQCAIN-UHFFFAOYSA-N
InChi: InChI=1S/C26H34ClN6O2P/c1-32(2)18-12-14-33(15-13-18)19-10-11-21(23(16-19)35-3)30-26-28-17-20(27)25(31-26)29-22-8-6-7-9-24(22)36(4,5)34/h6-11,16-18H,12-15H2,1-5H3,(H2,28,29,30,31)
Smiles: CN(C)C1CCN(CC1)C1=CC(OC)=C(C=C1)NC1N=C(NC2C=CC=CC=2P(C)(C)=O)C(Cl)=CN=1
Purity: 98.0
Solubility: Soluble in DMSO, not in water
Appearance: Solid Power.
Shelf Life: 1.0 years
Formula: C26 H34 Cl N6 O2 P
CAS Number: 1197958-12-5
InChi Key: OVDSPTSBIQCAIN-UHFFFAOYSA-N
InChi: InChI=1S/C26H34ClN6O2P/c1-32(2)18-12-14-33(15-13-18)19-10-11-21(23(16-19)35-3)30-26-28-17-20(27)25(31-26)29-22-8-6-7-9-24(22)36(4,5)34/h6-11,16-18H,12-15H2,1-5H3,(H2,28,29,30,31)
Smiles: CN(C)C1CCN(CC1)C1=CC(OC)=C(C=C1)NC1N=C(NC2C=CC=CC=2P(C)(C)=O)C(Cl)=CN=1
Purity: 98.0
Solubility: Soluble in DMSO, not in water
Appearance: Solid Power.
Shelf Life: 1.0 years
Description:
Brigatinib-analog is an orally active, potent and selective anaplastic lymphoma kinase (ALK) and the epidermal growth factor receptor (EGFR) inhibitor. Brigatinib-analog is structurally related to Brigatinib (AP-26113). Brigatinib-analog binds to and inhibits ALK kinase and ALK fusion proteins as well as EGFR and mutant forms. This leads to the inhibition of ALK kinase and EGFR kinase, disrupts their signaling pathways and eventually inhibits tumor cell growth in susceptible tumor cells.
Size: 10mg, 2mg
Applications: Life Science
For research use only. Not intended for diagnostic or therapeutic use.