bs-7106R [Primary Antibody]
NUPR1 Polyclonal Antibody
www.biossusa.com
[email protected]
800.501.7654 [DOMESTIC]
+1.781.569.5821 [INTERNATIONAL]
DATASHEET

Host: Rabbit

Target Protein: NUPR1

Immunogen Range: 31-82/82


Clonality: Polyclonal

Isotype: IgG

Entrez Gene: 26471

Source: KLH conjugated synthetic peptide derived from human NUPR1/p8

Purification: Purified by Protein A.

Storage Buffer: 0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Storage: Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.

Background:

Could participate in the response to proapoptotic stimuli and promotes cellular growth in a way that helps the tissue counteract diverse injuries. May contribute to the metastatic phenotype.Tissue specificity: Highly expressed in pancreas.

Size: 100ul

Concentration: 1ug/ul

Applications: WB(1:300-5000)
ELISA(1:500-1000)
IHC-P(1:200-400)

Predicted Molecular Weight: 9


Cross Reactive Species: Human
Mouse

Predicted Cross Reactive Species: Rat
Dog
Cow
Sheep
Horse

For research use only. Not intended for diagnostic or therapeutic use.

PRODUCT SPECIFIC PUBLICATIONS
  • Narzt et al. A novel role for NUPR1 in the keratinocyte stress response to UV oxidized phospholipids. (2018) Redox.Biol. 20:467-482Read more>>
  • Shiraki M et al. Deficiency of stress-associated gene Nupr1 increases bone volume by attenuating differentiationof osteoclasts and enhancing differentiation of osteoblasts. FASEB J. 2019 May 8:fj201802322RR. Read more>>
  • Li Tan. et al. Dietary saturated fatty acid palmitate promotes cartilage lesions and activates the unfolded protein response pathway in mouse knee joints. Plos One. 2021 Feb;16(2):e0247237Read more>>
  • Li Tan. et al. Age-Related Decline in Expression of Molecular Chaperones Induces Endoplasmic Reticulum Stress and Chondrocyte Apoptosis in Articular Cartilage. Aging Dis. 2020 Oct; 11(5): 1091C1102Read more>>
  • Yanxin Li. et al. Decoding the temporal and regional specification of microglia in the developing human brain. Cell Stem Cell. 2022 MaRead more>>
  • Li Tan. et al. Nuclear protein-1 is the common link for pathways activated by aging and obesity in chondrocytes: A potential therapeutic target for osteoarthritis. FASEB J. 2023 Aug;37(9):e23133Read more>>
  • Zhou Jie. et al. Nupr1-mediated vascular smooth muscle cell phenotype transformation involved in methamphetamine induces pulmonary hypertension. CELL BIOL TOXICOL. 2024 Dec;40(1):1-2Read more>>
VALIDATION IMAGES

Lane 1: Human L-O2 cell lysates; Lane 2: Human U87MG cell lysates probed with NUPR1 Polyclonal Antibody, Unconjugated (bs-7106R) at 1:1000 dilution and 4°C overnight incubation. Followed by conjugated secondary antibody incubation at 1:20000 for 60 min at 37˚C.