bs-7165C
[Life Science]
DCLK1-IN-1
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support@biossusa.com
800.501.7654 [DOMESTIC]
+1.781.569.5821 [INTERNATIONAL]
DATASHEET
Formulation powder
Storage: Store in dry, dark place at -20C for 1 year.
Product Information:
Molecular Weight: 527.54
Formula: C26 H28 F3 N7 O2
CAS Number: 2222635-15-4
InChi Key: OQFCHSFVWSLDAO-UHFFFAOYSA-N
InChi: InChI=1S/C26H28F3N7O2/c1-33-10-12-35(13-11-33)17-8-9-19(22(14-17)38-3)31-25-30-15-21-23(32-25)34(2)20-7-5-4-6-18(20)24(37)36(21)16-26(27,28)29/h4-9,14-15H,10-13,16H2,1-3H3,(H,30,31,32)
Smiles: CN1CCN(CC1)C1=CC(OC)=C(C=C1)NC1=NC2=C(C=N1)N(CC(F)(F)F)C(=O)C1C=CC=CC=1N2C
Purity: 98.0
Solubility: Soluble in DMSO
Appearance: Solid Power.
Shelf Life: 1.0 years
Formula: C26 H28 F3 N7 O2
CAS Number: 2222635-15-4
InChi Key: OQFCHSFVWSLDAO-UHFFFAOYSA-N
InChi: InChI=1S/C26H28F3N7O2/c1-33-10-12-35(13-11-33)17-8-9-19(22(14-17)38-3)31-25-30-15-21-23(32-25)34(2)20-7-5-4-6-18(20)24(37)36(21)16-26(27,28)29/h4-9,14-15H,10-13,16H2,1-3H3,(H,30,31,32)
Smiles: CN1CCN(CC1)C1=CC(OC)=C(C=C1)NC1=NC2=C(C=N1)N(CC(F)(F)F)C(=O)C1C=CC=CC=1N2C
Purity: 98.0
Solubility: Soluble in DMSO
Appearance: Solid Power.
Shelf Life: 1.0 years
Description:
DCLK1-IN-1, also known as OUN35154, is a selective, oral bioavailability in vivo-compatible chemical probe of the doublecortin like kinase 1 (DCLK1 kinase) domain. CLK1-IN-1 inhibits DCLK1 and DCLK2 kinases (IC50: DCLK1=9.5/57.2 nM and DCLK2=31/103 nM in binding and kinase assay, respectively). DCLK1-IN-1 will serve as a versatile tool to study DCLK1 biol. and establish its role in cancer.
Size: 10mg, 2mg
Applications: Life Science
For research use only. Not intended for diagnostic or therapeutic use.