bs-75971C

DATASHEET

Formulation Powder

Storage: Stable for 2 years after receipt when stored at -20°C.

Product Information:

CAS Number: 576-19-2

Molecular formula: C16H28N4O4S

Molecular weight: 372.48

Purity: >95% (NMR)

Appearance: White to off-white powder.

Solubility: Soluble in PBS or water (20 mg/ml). We do not recommend to store aqueous solutions for more than one day.

InChiKey: BAQMYDQNMFBZNA-WBGPXRNDSA-N

SMILES: [H][C@]12CS[C@@H](CCCCC(NCCCCC(N)C(O)=O)=O)[C@@]1([H])NC(N2)=O

Description:

Biocytin is a conjugate of biotin and lysine known formally as epsilon-N-(d-biotinyl)-L-lysine. The addition of lysine to biotin increases the chain length extending from biotin, allowing the synthesis of medium-chain reagents. It also provides terminal carboxyl and amino groups for derivatization or conjugation to proteins and other molecules. Covalent linking reactions typically involve carbodiimide or NHS-ester crosslinking chemistries. Biocytin is also used as an anterograde, retrograde, or intracellular neuroanatomical tracer that is fixable with aldehyde-based fixatives. It is also used in biotinidase assays. Biocytin may be injected into brain by iontophoresis or by pressure injection methods, and localized in tissue sections using avidin-conjugated labels.