bs-76083C
[Life Science]
Corilagin
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support@biossusa.com
800.501.7654 [DOMESTIC]
+1.781.569.5821 [INTERNATIONAL]
support@biossusa.com
800.501.7654 [DOMESTIC]
+1.781.569.5821 [INTERNATIONAL]
DATASHEET
Formulation Powder
Storage: Stable for 2 years after receipt when stored at +4°C.
Product Information:
CAS Number: 23094-69-1
Molecular formula: C27H22O18
Molecular weight: 634.45
Purity: >98% (HPLC)
Appearance: White to off-white powder.
Solubility: Soluble in DMSO, DMF or ethanol (all 20mg/ml). Slightly soluble in water (1mg/ml).
InChiKey: TUSDEZXZIZRFGC-XIGLUPEJSA-N
SMILES: O=C(O[C@H]([C@H]1O)[C@H](O)[C@H](O[C@H]1OC(C2=CC(O)=C(O)C(O)=C2)=O)COC3=O)C4=CC(O)=C(O)C(O)=C4C5=C3C=C(O)C(O)=C5O
Molecular formula: C27H22O18
Molecular weight: 634.45
Purity: >98% (HPLC)
Appearance: White to off-white powder.
Solubility: Soluble in DMSO, DMF or ethanol (all 20mg/ml). Slightly soluble in water (1mg/ml).
InChiKey: TUSDEZXZIZRFGC-XIGLUPEJSA-N
SMILES: O=C(O[C@H]([C@H]1O)[C@H](O)[C@H](O[C@H]1OC(C2=CC(O)=C(O)C(O)=C2)=O)COC3=O)C4=CC(O)=C(O)C(O)=C4C5=C3C=C(O)C(O)=C5O
Description:
Corilagin is a polyphenol and hydrolyzable tannin that can be isolated from a variety of plants. It inhibits squalene epoxidase, a key enzyme in cholesterol synthesis and has various anti-inflammatory and anti-cancer effects. This compound displays the ability to inhibit NF-kappaB pathway activation and also prevent the release of TNF-alpha. Additional studies show that Corilagin significantly inhibits type 1 plasminogen activator inhibitor (PAI-1) in rat plasma. Shown to have antioxidant, antiviral and hepatoprotective properties. Induces apoptosis, autophagy and ROS generation in several cell lines.
Size: 10mg, 50mg
Applications: Life Science
For research use only. Not intended for diagnostic or therapeutic use.