DATASHEET
Formulation
Powder
Storage:
Stable for 2 years after receipt when stored at -20°C.
Product Information:
CAS Number: 14348-21-1
Molecular formula: C21H22O5
Molecular weight: 354.4
Purity: >98% (HPLC)
Appearance: Light yellow powder.
Solubility: Soluble in DMSO.
InChiKey: HJMDOAWWVCOEDW-UHFFFAOYSA-N
SMILES: C/C(C)=C/COC1=C2C(OC(C=C2)=O)=C(OC/C=C(C)/C)C3=C1C=CO3
Description:
Cnidicin is a natural product isolated from the root extract of Angelica koreana (Umbelliferae). Cnidicin has anti-allergic and anti-inflammatory activity. It inhibits the degranulation of mast cell and the nitric oxide (NO) generation in RAW 264.7 cells, by inhibition of nitric oxide synthase expression. Cnidicin has shown anti-proliferative and cytotoxic activity in vitro on cultured human tumor cells such as A549 (non small cell lung), SK-OV-3 (ovary), SK-MEL-2 (melanoma), XF498 (central nervous system) and HCT-15 (colon).