DATASHEET
Formulation
Solid
Storage:
Stable for 2 years after receipt when stored at -20°C.
Product Information:
CAS Number: 143503-03-1
Molecular formula: C20H16N2O5
Molecular weight: 364.35
Purity: >97% (HPLC)
Appearance: Solid.
Solubility: Soluble in DMSO.
InChiKey: ISCHQGBNSNVWCQ-UHFFFAOYSA-N
SMILES: COC1=C(OC)C=C2C(CN(C2=O)C2=CC=C(C=C2)N2C(=O)C=CC2=O)=C1
SMILES: COC1=C(OC)C=C2C(CN(C2=O)C2=CC=C(C=C2)N2C(=O)C=CC2=O)=C1
Description:
Nonfluorescent N-substituted maleimides react selectively with thiol compounds to form fluorescent derivatives. Fluorescent intensity of the dimethoxyphthalimidyl group is higher than that of the nonsubsituted phthalimidyl group. The analytical sensitivity of N-[4-(5,6-Dimethoxy-N-phthalimidyl)phenyl]maleimide (DPM) is about 3-times higher than that of N-[4-(2-phthalimidyl)phenyl]maleimide (PPM). DPM can be used as a precolumn labeling reagent in HPLC. DPM was also used for the determination of physiologically important thiols in biological fluids or therapeutic drug monitoring.