DATASHEET
Formulation
Solid
Storage:
Stable for 2 years after receipt when stored at -20°C.
Product Information:
CAS Number: 74515-25-6
Molecular formula: C24H35NO
Molecular weight: 353.54
Purity: >97% (HPLC)
Appearance: Light yellow solid.
Solubility: Soluble in methanol, DMF or acetonitrile.
InChiKey: JHDGGIDITFLRJY-UHFFFAOYSA-N
SMILES: CCCCCCCCCCCC(=O)C1=CC2=CC=C(C=C2C=C1)N(C)C
SMILES: CCCCCCCCCCCC(=O)C1=CC2=C(C=C1)C=C(C=C2)N(C)C
Description:
N,N-Dimethyl-6-dodecanoyl-2-naphthylamine (Laurdan) is used as an environmentally sensitive probe for the labeling of plasma membranes. The lauroyl-sidechain integrates into the hydrophobic core of biological membranes, the polar fluorescent moiety is at level of the glycerol-backbone. Dipolar relaxation processes of the naphtylamine-moiety with neighboring polar molecules lead to wavelength-shifts of the emission-spectra. The physical state of the membrane and effects of temperature, cholesterol or ethanol on various membrane-systems have been monitored.