DATASHEET
Formulation
Powder
Storage:
Stable for 2 years after receipt when stored at -20°C.
Product Information:
CAS Number: 1456890-74-6
Molecular formula: C18H24N2O6
Molecular weight: 364.39
Purity: >95% (NMR)
Appearance: Light yellow powder.
Solubility: Soluble in DMSO or water.
InChiKey: YGMFXQGOHXJXGN-UHFFFAOYSA-N
SMILES: O=C(C(C1=O)=CC2=C(O1)C=C(N(CC)CC)C=C2)NC(CO)(CO)CO
Description:
Coumarin-based 'turn-off' fluorescent probe. Highly selective for ferrous ions (Fe(2+)) and can reversibly detect them in aqueous medium. The probe localizes to the cell membrane in living cells, where it can detect changes in Fe(2+) concentration. Molecular dynamics (MD) simulations indicate that AGD interacts with the lipid bilayer at the level of the glycerol moieties. Spectral data: Excitation=430nm; Emission=480nm (HEPES, pH 7.4 at RT).