DATASHEET
Formulation
Solid
Storage:
Stable for 2 years after receipt when stored at +4°C.
Product Information:
CAS Number: 938-55-6
Molecular formula: C7H9N5
Molecular weight: 163.18
Purity: >97% (HPLC)
Appearance: White solid.
Solubility: Soluble in DMF.
InChiKey: BVIAOQMSVZHOJM-UHFFFAOYSA-N
SMILES: CN(C)C1=C2NC=NC2=NC=N1
SMILES: CN(C)C1=NC=NC2=C1NC=N2
Description:
A puromycin analog that acts as a protein kinase inhibitor. Selectively induces premature mitosis in mammalian cells. Inhibits TNF-alpha upregulation of ICAM-1, lipolysis, and the activation of JNK/SAPK. Inhibits p34cdc2/cyclin B (IC50 = 300 µM). Induces apoptosis in S-phase-arrested HeLa cells (~5 mM).