bs-76211C
[Life Science]
N-Dodecanoyl-DL-homoserine lactone
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support@biossusa.com
800.501.7654 [DOMESTIC]
+1.781.569.5821 [INTERNATIONAL]
DATASHEET
Formulation Solid
Storage: Stable for 2 years after receipt when stored at +4°C.
Product Information:
CAS Number: 18627-38-8
Molecular formula: C16H29NO3
Molecular weight: 283.4
Purity: >97% (GC)
Appearance: White solid.
Solubility: Soluble in chloroform.
InChiKey: WILLZMOKUUPJSL-UHFFFAOYSA-N
SMILES: CCCCCCCCCCCC(=O)NC1CCOC1=O
SMILES: CCCCCCCCCCCC(=O)NC1CCOC1=O
Molecular formula: C16H29NO3
Molecular weight: 283.4
Purity: >97% (GC)
Appearance: White solid.
Solubility: Soluble in chloroform.
InChiKey: WILLZMOKUUPJSL-UHFFFAOYSA-N
SMILES: CCCCCCCCCCCC(=O)NC1CCOC1=O
SMILES: CCCCCCCCCCCC(=O)NC1CCOC1=O
Description:
N-Dodecanoyl-DL-homoserine lactone (C12-HSL) is a small diffusible signalling molecule involved in quorum sensing, thereby controlling gene expression and affecting cellular metabolism in bacteria. In addition to regulating bacterial functions, C12-HSL activates NF-kappaB in RAW 264.7 macrophages, increasing the expression of TNF-alpha, interleukin-1beta (IL-1beta) and IL-8, while other lactones do not. In addition, C12-HSL alters cell cycling and metabolism of human keratinocyte (HaCaT) cells. It also was shown to induce cell death by apoptosis.
Size: 10mg,50mg
Applications: Life Science()
For research use only. Not intended for diagnostic or therapeutic use.