bs-76226C

DATASHEET

Formulation Powder

Storage: Stable for 2 years after receipt when stored at +20°C.

Product Information:

CAS Number: 59-92-7

Molecular formula: C9H11NO4

Molecular weight: 197.19

Purity: >98%

Appearance: White to off-white powder.

Solubility: Soluble in water (5-10mM), acidic and basic solutions.

InChiKey: WTDRDQBEARUVNC-LURJTMIESA-N

SMILES: OC1=C(O)C=CC(C[C@H](N)C(O)=O)=C1

SMILES: N[C@@H](CC1=CC=C(O)C(O)=C1)C(O)=O

Description:

Metabolic precursor of the neurotransmitters dopamine, norepinephrine (noradrenaline), and epinephrine (adrenaline), which are collectively known as catecholamines. This amino acid is produced from L-tyrosine by tyrosine hydroxylase and metabolized by catechol-O-methyl transferase (COMT). L-DOPA is capable of crossing the blood brain barrier where it is converted to dopamine. Formulations containing L-DOPA have been used to increase dopamine concentrations in the brain as a treatment for Parkinson’s disease and stroke recovery. Mediates neurotrophic factor release by the brain and CNS. Used for the treatment of Parkinson’s disease and dopamine-responsive dystonia. In addition it is used, as a cell adhesion molecule in serum-free cultures of anchorage-dependent mammalian cells, to prevent surfaces from fouling by bonding antifouling polymers to a susceptible substrate or to stain melanocytes.