bs-76232C

DATASHEET

Formulation Powder

Storage: Stable for 2 years after receipt when stored at +4°C.

Product Information:

CAS Number: 19408-84-5

Molecular formula: C18H29NO3

Molecular weight: 307.43

Purity: >97% (HPLC)

Appearance: White to off-white powder.

Solubility: Soluble in ethanol, DMSO or DMF (30mg/ml).

InChiKey: XJQPQKLURWNAAH-UHFFFAOYSA-N

SMILES: OC1=C(OC)C=C(CNC(CCCCCCC(C)C)=O)C=C1

SMILES: COC1=C(O)C=CC(CNC(=O)CCCCCCC(C)C)=C1

Description:

Dihydrocapsaicin is a capsaicinoid and analog and congener of capsaicin in chili peppers (capsicum). Dihydrocapsaicin accounts for about 10% of the total capsaicinoid mixture and separation by HPLC is required in order to obtain pure dihydrocapsaicin. Dihydrocapsaicin, similar as capsaicin elicits a sensation of burning pain by activation of VR1 on small, non-myelinated polymodal C-type nociceptive nerve fibers. VR1 (vanilloid receptor 1) is a heat activated calcium ion channel which functions as a part of the normal nociceptive pain pathway. Shown to be analgesic against arthritis pain and inflammation and protective effects against high cholesterol levels and obesity. Induced autophagy, apoptosis in glioma cells via ROS-dependent pathways.