DATASHEET
Formulation
Powder
Storage:
Stable for 2 years after receipt when stored at +4°C.
Product Information:
CAS Number: 57808-66-9
Molecular formula: C22H24ClN5O2
Molecular weight: 425.91
Purity: >98% (HPLC)
Appearance: White powder.
Solubility: Soluble in DMSO (10mg/ml).
InChiKey: FGXWKSZFVQUSTL-UHFFFAOYSA-N
SMILES: ClC1=CC(NC2=O)=C(C=C1)N2C(CC3)CCN3CCCN(C4=CC=CC=C4N5)C5=O
SMILES: ClC1=CC2=C(C=C1)N(C1CCN(CCCN3C(=O)NC4=C3C=CC=C4)CC1)C(=O)N2
Description:
Domperidone is a peripheral dopamine D2-like receptor antagonist that does not readily cross the blood-brain barrier. It demonstrates a potent affinity for the rat D2 receptor and is also reported to inhibit the rat D3 receptor. The antidopaminergic effects are cross-realted to its gastroprokinetic and antiemetic properties.