bs-76250C
[Life Science]
Demethoxycurcumin
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support@biossusa.com
800.501.7654 [DOMESTIC]
+1.781.569.5821 [INTERNATIONAL]
DATASHEET
Formulation Powder
Storage: Stable for 2 years after receipt when stored at +4°C.
Product Information:
CAS Number: 22608-11-3
Molecular formula: C20H18O5
Molecular weight: 338.35
Purity: >98% (HPLC)
Appearance: Yellow to orange powder.
Solubility: Soluble in DMSO (10mg/ml) or DMF (10mg/ml).
InChiKey: HJTVQHVGMGKONQ-LUZURFALSA-N
SMILES: OC1=CC=C(/C=C/C(CC(/C=C/C2=CC=C(O)C(OC)=C2)=O)=O)C=C1
Molecular formula: C20H18O5
Molecular weight: 338.35
Purity: >98% (HPLC)
Appearance: Yellow to orange powder.
Solubility: Soluble in DMSO (10mg/ml) or DMF (10mg/ml).
InChiKey: HJTVQHVGMGKONQ-LUZURFALSA-N
SMILES: OC1=CC=C(/C=C/C(CC(/C=C/C2=CC=C(O)C(OC)=C2)=O)=O)C=C1
Description:
Demethoxycurcumin (DMC) is a natural demethoxy derivative of curcumin with anti-inflammatory and anti-cancer properties. DMC suppresses cell proliferation, migration and invasion in cancer cells. It down-regulates the transcriptional coactivator p300, suppressing the Wnt/beta-catenin pathway, and inhibits lipopolysaccharide induction of iNOS by blocking NF-kappa activation. It also has been shown to inhibit energy metabolic and oncogenic signaling pathways through AMPK activation. In addition it is a potent inhibitor of P-Type ATPases. Shown to have neuroprotective properties. It also has anti-plasmodial activity.
Size: 5mg,25mg
Applications: Life Science()
For research use only. Not intended for diagnostic or therapeutic use.