bs-76280C
[Life Science]
Ethionamide
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support@biossusa.com
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support@biossusa.com
800.501.7654 [DOMESTIC]
+1.781.569.5821 [INTERNATIONAL]
DATASHEET
Formulation Powder
Storage: Stable for 2 years after receipt when stored at +4°C.
Product Information:
CAS Number: 536-33-4
Molecular formula: C8H10N2S
Molecular weight: 166.24
Purity: >98% (HPLC)
Appearance: Yellow powder.
Solubility: Soluble in DMSO (10mg/ml) or ethanol (5mg/ml).
InChiKey: AEOCXXJPGCBFJA-UHFFFAOYSA-N
SMILES: NC(C1=CC(CC)=NC=C1)=S
SMILES: CCC1=NC=CC(=C1)C(N)=S
Molecular formula: C8H10N2S
Molecular weight: 166.24
Purity: >98% (HPLC)
Appearance: Yellow powder.
Solubility: Soluble in DMSO (10mg/ml) or ethanol (5mg/ml).
InChiKey: AEOCXXJPGCBFJA-UHFFFAOYSA-N
SMILES: NC(C1=CC(CC)=NC=C1)=S
SMILES: CCC1=NC=CC(=C1)C(N)=S
Description:
Ethionamide is an antimycobacterial antibiotic that is active against M. tuberculosis (MICs = 0.3-1.25 µg/ml). Ethionamide is a prodrug activated via oxidation by ethA (a flavin monooxygenase) and leading to the formation of an soxide metabolite, which inhibits the InhA enzyme involved in mycolic acid biosynthesis. Formulations containing ethionamide have been used in the second-line treatment of multi-drug resistant tuberculosis. Ethionamide inhibits both biofilm formation and viability of mature biofilms. Ethionamide is a thioamide analog of the first-line tuberculosis drug isoniazid.
Size: 5g,25g,100g
Applications: Life Science()
For research use only. Not intended for diagnostic or therapeutic use.