bs-76318C [Life Science]
5-Fluorocytosine
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Formulation Powder

Storage: Stable for 2 years after receipt when stored at -20°C.

Product Information:

CAS Number: 2022-85-7

Molecular formula: C4H4FN3O

Molecular weight: 129.09

Purity: >99% (TLC)

Appearance: White to off-white powder.

Solubility: Soluble in water.

InChiKey: XRECTZIEBJDKEO-UHFFFAOYSA-N

SMILES: NC1=NC(=O)NC=C1F

SMILES: NC1=NC(=O)NC=C1F

Description:

Fluorinated pyrimidine analog. Antimycotic prodrug that is converted by cytosine deaminase to 5-fluorouracil (a widely used cytotoxic drug) and further metabolized to fluorinated ribo- and deoxyribonucleotides. Inhibits DNA and RNA synthesis and interfers with ribosomal protein synthesis. Displays antifungal and antitumor activity. Lately with the development of gene therapy, it has been introduced as a prodrug in combination with the cytosine deaminase suicide gene as antitumor compound, significantly improving survival and reducing tumor size in selected tumors.

Size: 1g,5g

Applications: Life Science()

For research use only. Not intended for diagnostic or therapeutic use.