bs-76342C
[Life Science]
Fluticasone propionate
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support@biossusa.com
800.501.7654 [DOMESTIC]
+1.781.569.5821 [INTERNATIONAL]
DATASHEET
Formulation Powder
Storage: Stable for 2 years after receipt when stored at RT.
Product Information:
CAS Number: 80474-14-2
Molecular formula: C25H31F3O5S
Molecular weight: 500.57
Purity: >97% (NMR)
Appearance: White powder.
Solubility: Soluble in DMSO (20mg/ml) or DMF (20mg/ml).
InChiKey: WMWTYOKRWGGJOA-CENSZEJFSA-N
SMILES: O[C@H]1C[C@@]2(C)[C@](C[C@@H](C)[C@]2(OC(CC)=O)C(SCF)=O)([H])[C@]3([H])C[C@H](F)C4=CC(C=C[C@]4(C)[C@]31F)=O
SMILES: [H][C@@]12C[C@@H](C)[C@](OC(=O)CC)(C(=O)SCF)[C@@]1(C)C[C@H](O)[C@@]1(F)[C@@]2([H])C[C@H](F)C2=CC(=O)C=C[C@]12C
Molecular formula: C25H31F3O5S
Molecular weight: 500.57
Purity: >97% (NMR)
Appearance: White powder.
Solubility: Soluble in DMSO (20mg/ml) or DMF (20mg/ml).
InChiKey: WMWTYOKRWGGJOA-CENSZEJFSA-N
SMILES: O[C@H]1C[C@@]2(C)[C@](C[C@@H](C)[C@]2(OC(CC)=O)C(SCF)=O)([H])[C@]3([H])C[C@H](F)C4=CC(C=C[C@]4(C)[C@]31F)=O
SMILES: [H][C@@]12C[C@@H](C)[C@](OC(=O)CC)(C(=O)SCF)[C@@]1(C)C[C@H](O)[C@@]1(F)[C@@]2([H])C[C@H](F)C2=CC(=O)C=C[C@]12C
Description:
Fluticasone propionate is a synthetic corticosteroid. It is a high affinity, selective glucocorticoid receptor agonist (Kd = 0.5nM). It is used as an anti-inflammatory agent for asthma. It has low systemic bioavailability and has been investigated for effectiveness as an inhaled or intranasal corticosteroid to reduce airflow obstruction related to asthma, allergic rhinitis and other airway diseases. It potently stimulates glucocorticoid receptor-mediated transactivation of gene expression and enhances human eosinophil apoptosis in vitro. It also potentiates KV1 channels (EC50 = 37nM).
Size: 5mg,25mg
Applications: Life Science()
For research use only. Not intended for diagnostic or therapeutic use.