bs-76368C

DATASHEET

Formulation Powder

Storage: Stable for 2 years after receipt when stored at -20°C.

Product Information:

CAS Number: 548-83-4

Molecular formula: C15H10O5

Molecular weight: 270.24

Purity: >98% (HPLC)

Appearance: Light yellow powder.

Solubility: Soluble in DMSO (20mg/ml), DMF (20mg/ml) or ethanol (10mg/ml).

InChiKey: VCCRNZQBSJXYJD-UHFFFAOYSA-N

SMILES: OC1=C2C(OC(C3=CC=CC=C3)=C(O)C2=O)=CC(O)=C1

SMILES: OC1=CC(O)=C2C(OC(=C(O)C2=O)C2=CC=CC=C2)=C1

Description:

Galangin is a flavonoid naturally found in herbs used in traditional medicine. It has diverse biological activities, including potent antioxidant, anti-inflammatory, antiobesity, antidiabetic, anti-cancer, neuroprotective, antiviral and antibacterial properties. Galangin has anti-inflammatory actions related to suppression of signaling through NF-kappa/NRLP3 pathway. Galangin induces apoptosis and autophagy in different cancer cells. It is a TRPC5 inhibitor, inhibiting Ca2+ entry into TRPC5 expressing cells. Galangin as a potential DPP-4 inhibitor that improves insulin-stimulated skeletal muscle glucose uptake.