bs-76437C

DATASHEET

Formulation Powder

Storage: Stable for 2 years after receipt when stored at -20°C.

Product Information:

CAS Number: 482-36-0

Molecular formula: C21H20O12

Molecular weight: 464.38

Purity: >98% (HPLC)

Appearance: Yellow powder.

Solubility: Soluble in DMSO (10mg/ml) or DMF (10mg/ml).

InChiKey: OVSQVDMCBVZWGM-DTGCRPNFSA-N

SMILES: O=C1C2=C(O)C=C(O)C=C2OC(C3=CC=C(O)C(O)=C3)=C1O[C@@H]4O[C@H](CO)[C@H](O)[C@H](O)[C@H]4O

SMILES: OC[C@H]1O[C@@H](OC2=C(OC3=CC(O)=CC(O)=C3C2=O)C2=CC(O)=C(O)C=C2)[C@H](O)[C@@H](O)[C@H]1O

Description:

Hyperoside is a 3-O-galactoside of quercetin that can be found in a wide range of plants. It shows diverse biological activities, including antioxidant, anti-inflammatory, neuroprotective, antihypoglycemic and antiadipogenic, antibacterial and anticancer properties. It has powerful antioxidant action through its ability to scavenge free radicals. It inhibits the NF-kappaB signaling pathway. Hyperoside selectively interrupted NLRC4 and AIM2 inflammasome activation but did not alter cytokine expression. The quorum sensing-inhibiting effect of hyperoside may lead to a reduction in biofilm formation in P. aeruginosa. Honokiol exerts broad-range anticancer activity, such as induction of apoptosis and autophagy and inhibition of cell proliferation. Hyperoside has a beneficial effect on the prevention and treatment of obesity.