bs-76468C [Life Science]
Isoorientin
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Formulation Powder

Storage: Stable for 2 years after receipt when stored at +4°C.

Product Information:

CAS Number: 4261-42-1

Molecular formula: C21H20O11

Molecular weight: 448.38

Purity: >98% (HPLC)

Appearance: Yellow powder.

Solubility: Soluble in DMSO (15mg/ml), DMF (15mg/ml) or methanol (5mg/ml).

InChiKey: ODBRNZZJSYPIDI-VJXVFPJBSA-N

SMILES: OC(C(C(C=C(C1=CC(O)=C(O)C=C1)O2)=O)=C2C=C3O)=C3[C@H]4[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O4

SMILES: OC[C@H]1O[C@H]([C@H](O)[C@@H](O)[C@@H]1O)C1=C(O)C2=C(OC(=CC2=O)C2=CC(O)=C(O)C=C2)C=C1O

Description:

Isoorientin is a flavonoid with various biological properties. It has anticancer, antioxidant, anti-inflammatory, antimicrobial, gastroprotective and antinociceptive activities. It induces apoptosis in and reduces cell viability of cancer cells. It is a selective Cyclooxygenase-2 (COX-2) inhibitor. Reduces expression of COX-2, IL-6, 5-lipoxygenase (5-LO), and TNF-alpha in RAW 264.7 cells. It also has shown to regulate lipid metabolism.

Size: 1mg, 5mg, 10mg

Applications: Life Science

For research use only. Not intended for diagnostic or therapeutic use.