DATASHEET
Formulation
Powder
Storage:
Stable for 2 years after receipt when stored at +4°C.
Product Information:
CAS Number: 74103-07-4
Molecular formula: C15H13NO3 . C4H11NO3
Molecular weight: 376.4
Purity: >99% (HPLC)
Appearance: White to off-white powder.
Solubility: Soluble in DMSO, DMF, water or methanol.
InChiKey: BWHLPLXXIDYSNW-UHFFFAOYSA-N
SMILES: O=C(C1=CC=CC=C1)C2=CC=C3N2CCC3C(O)=O.OCC(CO)(CO)N
SMILES: NC(CO)(CO)CO.OC(=O)C1CCN2C1=CC=C2C(=O)C1=CC=CC=C1
Description:
Ketorolac is a non-steroidal anti-inflammatory drug (NSAID) to treat pain. It is a non-selective COX inhibitor (IC50 = 20nM for both COX-1 and COX-2), thereby decreasing prostaglandins. Ketorolac is a racemic mixture containing the active (S)-ketorolac and inactive (R)-ketorolac enantiomers. Formulations containing ketorolac have been used to manage postoperative pain and as ophthalmic solutions to treat ocular pain and inflammation.