bs-76487C [Life Science]
Levocetirizine dihydrochloride
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Formulation Solid

Storage: Stable for 2 years after receipt when stored at RT.

Product Information:

CAS Number: 130018-87-0

Molecular formula: C21H25ClN2O3 . 2HCl

Molecular weight: 461.81

Purity: >98% (HPLC)

Appearance: Solid.

Solubility: Soluble in water (20mg/ml).

InChiKey: PGLIUCLTXOYQMV-GHVWMZMZSA-N

SMILES: ClC(C=C1)=CC=C1[C@@H](C2=CC=CC=C2)[NH+]3CC[NH+](CCOCC(O)=O)CC3.[Cl-].[Cl-]

SMILES: Cl.Cl.OC(=O)COCCN1CCN(CC1)[C@H](C1=CC=CC=C1)C1=CC=C(Cl)C=C1

Description:

Levocetirizine hydrochloride is the (R)-enantiomer of the histamine H1 receptor antagonist and antihistamine agent cetirizine. It binds to the H1 receptor with higher affinity than cetirizine and is 25,000-100,000-fold selective for H1 receptors over muscarinic M1-M5 receptors. Intranasal administration dose-dependently decreases histamine-induced nasal rubbing and sneezing in mice. Has been used in the treatment of allergic rhinitis and chronic idiopathic urticaria.

Size: 10mg, 50mg

Applications: Life Science

For research use only. Not intended for diagnostic or therapeutic use.