bs-7663R-A647 [Conjugated Primary Antibody]
MDM4 POLYCLONAL ANTIBODY, ALEXA FLUOR® 647 Conjugated
www.biossusa.com
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DATASHEET

Host: Rabbit

Target Protein: MDM4

Immunogen Range: 301-400/490


Clonality: Polyclonal

Isotype: IgG

Entrez Gene: 4194

Swiss Prot: O15151

Source: KLH conjugated synthetic peptide derived from human MDM4

Purification: Purified by Protein A.

Storage Buffer: Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Storage: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Background:

Inhibits p53/TP53- and TP73/p73-mediated cell cycle arrest and apoptosis by binding its transcriptional activation domain. Inhibits degradation of MDM2. Can reverse MDM2-targeted degradation of TP53 while maintaining suppression of TP53 transactivation and apoptotic functions.

Conjugation: ALEXA FLUOR® 647

Excitation/ Emission: 650nm/665nm

Size: 100ul

Concentration: 1ug/ul

Applications: WB(1:300-5000)
IF(IHC-P)(1:50-200)
IF(IHC-F)(1:50-200)
IF(ICC)(1:50-200)

Predicted Molecular Weight: 55


Cross Reactive Species: Mouse

Predicted Cross Reactive Species: Human
Rat
Dog
Cow
Sheep
Pig
Horse
Rabbit

For research use only. Not intended for diagnostic or therapeutic use.

PRODUCT SPECIFIC PUBLICATIONS
  • Jiahui Dong. et al. Verbenalin attenuates hepatic damage and mitochondrial dysfunction in alcohol-associated steatohepatitis by regulating MDMX/PPAR-mediated ferroptosis. J ETHNOPHARMACOL. 2023 Feb;:116227Read more>>
VALIDATION IMAGES