bs-76724C
[Life Science]
(+/-)-Propranolol hydrochloride
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support@biossusa.com
800.501.7654 [DOMESTIC]
+1.781.569.5821 [INTERNATIONAL]
DATASHEET
Formulation Powder
Storage: Stable for 2 years after receipt when stored at +4°C.
Product Information:
CAS Number: 318-98-9
Molecular formula: C16H21NO2 . HCl
Molecular weight: 295.8
Purity: >99% (TLC)
Appearance: White powder.
Solubility: Soluble in DMSO (15mg/ml), ethanol (10mg/ml) or water (20mg/ml). Aqueous solutions are most stable at pH 3.0 and decompose rapidly at basic pH. Decomposition is accompanied by discoloration of the solution.
InChiKey: ZMRUPTIKESYGQW-UHFFFAOYSA-N
SMILES: OC(CNC(C)C)COC1=CC=CC2=CC=CC=C21.Cl
SMILES: Cl.CC(C)NCC(O)COC1=CC=CC2=C1C=CC=C2
Molecular formula: C16H21NO2 . HCl
Molecular weight: 295.8
Purity: >99% (TLC)
Appearance: White powder.
Solubility: Soluble in DMSO (15mg/ml), ethanol (10mg/ml) or water (20mg/ml). Aqueous solutions are most stable at pH 3.0 and decompose rapidly at basic pH. Decomposition is accompanied by discoloration of the solution.
InChiKey: ZMRUPTIKESYGQW-UHFFFAOYSA-N
SMILES: OC(CNC(C)C)COC1=CC=CC2=CC=CC=C21.Cl
SMILES: Cl.CC(C)NCC(O)COC1=CC=CC2=C1C=CC=C2
Description:
(±)-Propranolol hydrochloride is a beta-adrenergic receptor (beta-AR) antagonist (Kds = 6.91, 0.832, and 117.49 nM for human beta1-, beta2- and beta3-ARs, respectively). It also acts as a non-specific 5-HT1/5-HT2 serotonin receptor antagonist, reducing tranylcypromine/L-tryptophan-induced hyperactivity in rats. (±)-Propranolol hydrochloride is useful as an antihypertensive drug, cardiac depressant and also in the treatment of angina pectoris. It decreases the effect of stress and exercise on heart by reducing the rate of contraction and conduction of impulse. It is known to competitively block the action of catecholamines.
Size: 25g,100g
Applications: Life Science()
For research use only. Not intended for diagnostic or therapeutic use.